The Dragons launch their RaboDirect PRO12 campaign with a trip to Musgrave Park to play 2011 Champions Munster on Friday September 2, the same evening the Blues travel to Edinburgh and the Ospreys and Scarlets host Leinster and Aironi respectively.
Welsh supporters have to wait until Round 4 (4 November) for the first taste of derby action, when the Dragons host the Blues and the Scarlets travel to the Liberty Stadium to play the Ospreys.
The usually festive derby fixtures remain with the Blues and the Dragons meeting at the Cardiff City Stadium and the Scarlets hosting the Ospreys on Friday December 23.
There is further derby action a week later as the Dragons play the Scarlets and the Ospreys and Blues meet in Swansea.